Neurontin
Active ingredient: Gabapentin
Neurontin, select dosage: 100mg/300mg/400mg/600mg
Neurontin is an antiepileptic agent that prevents an abnormal surge of electrical activity in one or more areas of the brain. Neurontin pills are used for:
- Management of partial (focal) seizures, occurring in epilepsy
- Treatment of neuropathic pain associated with dysfunction of the somatosensory nervous system
Monotherapy with Neurontin is indicated to patients over 12 years old, suffering from partial seizures, including cases when this pathology is caused by secondary generalization. The drug may also be prescribed as a part of the combined antiepileptic therapy to patients older than 3 years.
The standard of care for the treatment of epilepsy in adults involves 900 to 3600mg of Neurontin per day. The treatment should be started with minimal doses of Neurontin. The daily dose of Neurontin can be gradually increased, but not more frequently than 2-3 times a week.
Neurontin dosage for children is indicated depending on the body weight and typically is from 25 to 50 mg/kg/day. The daily dose of Neurontin for children and adults needs to be spaced by three separate doses and taken at regular intervals.
Missed dose
If you have not taken antiepileptic agent Neurontin in time, use it as soon as you remember. But if the next intake should be in less than 4 hours, do not take Neurontin. You should remember that the drug intakes should be spaced by 12 hour intervals between doses.
More Information
Epilepsy and neuropathic pain often require a long-term treatment. Usually Neurontin is recommended to be used under 5 months, but if necessary, the treatment duration can be increased.
Neuropathic pain is a special type of pain that appears due to pathological excitation of neurons in the central or peripheral nervous system. These systems are responsible for the body’s pain response to physical stress. However, neuropathic pain has a specific mechanism of development when pain occurs without any reason or to minor stimuli.
People who are faced with this condition have a lot of questions. How to cope with such pain? What medications most effectively relieve unpleasant symptoms? What is the cost of treatment and is it possible to find a cheap drug that is still highly effective? To answer these questions, it is necessary to understand the characteristics of the disease itself, why it occurs, and what treatment methods are currently used.
Overview of Neuropathic Pain
Neuropathic pain may be constant or occur occasionally. In the second case, the attacks feel piercing or similar to electric shocks.
Common symptoms of neuropathic pain:
- burning;
- sensation of goosebumps on the skin;
- shooting pain;
- cutting pain;
- tingling;
- cold;
- numbness;
- itching.
Neuropathic pain most often has a chronic course and occurs in 7–8% of the population, while in 5% of people it is severe.
Causes of neuropathic pain
The causes of neuropathic pain may be the following factors, which subsequently influence the diagnosis:
- pathological processes in the peripheral nervous system (peripheral neuropathic);
- disturbances in the functioning of the central nervous system (neuropathy of central origin).
- pathologies of mixed type (neuropathy of mixed origin).
Features of manifestations of neuropathic pain
This disease is characterized by a complex of sensory disorders of specific manifestations. They can be divided into two groups:
- Positive:
- spontaneous symptoms (pain, abnormal sensations, paresthesia);
- evoked symptoms (hyperpathy, pain due to minor stimuli, hyperalgesia, hyperesthesia);
- Negative symptoms (hypesthesia, hypalgesia).
With neuropathic pain, positive and negative symptoms occur in various combinations and change in the same patient during the course of the disease.
Neuropathic pain is characterized by the appearance of painful sensations of varying intensity in response to the slightest touch, sometimes even to a blow of wind. This phenomenon is called allodynia.
Features of allodynia in neuropathic pain
Allodynia occurs:
- Temperature.
- Mechanical:
• static;
• dynamic. - Static allodynia occurs when pressure is applied to a certain area of the skin. Dynamic occurs with moving stimuli, for example, if you run your hand over the skin.
Main characteristics of the development of neuropathic pain
When people experience prolonged unreasonable pain, they cannot cope with it on their own and visit a specialist who conducts diagnostics and makes a diagnosis based on the following criteria:
- the person did not have injuries, inflammation or ischemia;
- pain is constant and persistent;
- pain is not relieved by painkillers;
- pain is localized in the area of the sensory defect, which corresponds to damage to a certain part of the nervous system;
- the presence of manifestations specific to neuropathic pain (hyperalgesia, allodynia, hyperesthesia, hyperpathia);
- the presence of autonomic disorders in the painful area (reduced blood flow, hypohidrosis, hyperhidrosis);
- presence of motor disorders;
- deterioration of health during sleep.
Patients with suspected neuropathic pain describe it as shooting, jerking, cutting, or burning. Also, some people note that the pain is similar to an electric shock.
Disorders that occur in patients with neuropathic pain
Patients with neuropathic pain typically have the following disorders:
- sleep disorders;
- depressive states of varying intensity;
- anxiety disorder.
However, the prevalence of depression or anxiety disorder in people with neuropathic pain is higher than in those who do not suffer from this disease. The quality of life of such patients is worse, and the pain intensity is higher. Anxiety can result from the stress of living with pain, and the pain itself can increase anxiety levels. Which in turn leads to an increase in the pain effect.
Features of the treatment of neuropathic pain
First, the doctor determines the severity of the disease, assesses the intensity of pain and its impact on quality of life. Further actions occur according to the following scheme:
- Prescription of drug treatment with explanations of why a particular drug or combination of drugs will be most effective.
- Explanation of the expected effect of therapy..
- Description of the most likely side effects.
- Cost of treatment.
- Explaining the importance of following the dosage of medications taken.
- Providing an individual scheme taking into account the patient’s health characteristics, with a detailed indication of all recommendations.
- Providing information on methods of dealing with stress when pain occurs.
If necessary, additional treatment methods are prescribed in addition to drug therapy (physiotherapy, surgery).
Drug therapy for neuropathic pain
Many patients at an appointment with a specialist are interested in which drug is best for them to buy? It is very important that it helps relieve pain and improves the quality of life. For all types of neuropathic pain (except for damage to the trigeminal nerve), the drug Gabapentin is highly effective. It is similar in structure to gamma-aminobutyric acid (GABA), which is found in the central nervous system. Gabapentin enhances the secretion of GABA and effectively blocks the mechanism that leads to neuropathic pain. Gabapentin also strengthens the muscular and nervous system.
Buy Gabapentin at a competitive price without a prescription
Gabapentin can be ordered from our online pharmacy without a doctor’s prescription. Why is its price lower than the market price? Because we provide an effective analog (generic) based on the active substance that is part of the original drug. Therefore, you can be sure that generic Gabapentin is no different from the drug that you can buy at a regular pharmacy.